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首页 > 产品详情 > 呼吸研究 > 雾化、给药、染毒仪器

动物暴露染毒系统

产品型号：

CIE-8080

详细介绍:

产品描述该系统为多功能暴露染毒系统，集成了全身暴露染毒和口鼻暴露染毒两种经典染毒方式。口鼻暴露染毒采用316L不锈钢特制的暴露塔对实验动 物进行暴露。集成式染毒... 查看详情 >
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产品描述

该系统为多功能暴露染毒系统，集成了全身暴露染毒和口鼻暴露染毒两种经典染毒方式。口鼻暴露染毒采用316L不锈钢特制的暴露塔对实验动 物进行暴露。集成式染毒舱可放置两个大鼠笼，系统独立监测控制每 个染毒舱内的环境。舱体为密闭式微负压设计，并具有废气处理装置， 配有多种废气处理单元，可以有效防止气溶胶泄漏到实验室或环境中。 舱体前后采用透明钢化玻璃，使用者可以从外面对动物进行观察，并且钢化玻璃耐腐蚀。具有全面的环境指标监测功能，可满足动物的居住和繁殖，并能对其进行长期暴露实验。

产品用途

  • 用于实验动物的染毒实验。适用各种形式的染毒物质，如化学气体(SO₂、NO₂、NH₃、H₂S、CO、O₃等)、药物气溶胶、粉尘气溶胶、PM2.5、香烟烟雾、汽车尾气等；

  • 多功能染毒方式：全身暴露式动态染毒、口鼻吸入暴露染毒；

  • 具有通风换气功能；

  • 密闭式微负压设计，完善的废气处理装置，全面的报警机制，保证实验安全；

  • 可直接将动物饲养笼放入染毒舱，也可选配个体不锈钢网笼；

  • 集成化设计，避免外置过多管路。

产品特点

  • 通过触摸屏操控，具有环境、染毒物质指标动态变化曲线；

  • 控制参数：染毒气体浓度、染毒时间等；

  • 集成化设计，方便维护；

  • 内置混匀风扇，使气体均匀分布在染毒舱；

  • 传感器舱监控舱内温度、湿度、氧气、二氧化碳、染毒气体浓度、压力。可选配安装气溶胶浓度检测器。


参考文献

[1]Fan Z,Zhou B,Liu Y,Sun W,Fang Y,Lu H,Chen D,Lu K,Wu X, Xiao T, Xie W, Bian Q."Optimization and Application of an Efficient and Stable Inhalation Exposure System for Rodents".[J].AAPS PharmSciTech.2022 Jan 6;23(1):50. doi:10.1208/s12249-021-02191-8.

[2]Jushan Zhang,Mo Xue,Rong Pan,Yujie Zhu,Zhongyang Zhang,Haoxiang Cheng,Johan L M Björkegren,Jia Chen,Zhiqiang Shi,Ke Hao"An e-cigarette aerosol generation, animal exposure and toxicants quantification system tocharacterize in vivo nicotine kinetics in arterial and venous blood"[J].bioRxiv preprint doi.

[3]Guolin Zhao,William Ho,Jinxian Chu, Xiaojian Xiong, Bin Hu,Kofi Oti Boakye-Yiadom,Xiaoyang Xu,Xue-Qing Zhang,Inhalable siRNA Nanoparticles for Enhanced Tumor-Targeting Treatment of KRAS-Mutant Non-Small-Cell Lung Cancer,[J]ACS Applied Materials&Interfaces,2023-06-24,DOI:10.1021/acsami.3c05007.

[4]Liu X, Zhao L, Wang R, et al. TRPM2 exacerbates airway inflammation by regulating oxidized-CaMKⅡ in allergic asthma[J]. Heliyon, 2024, 10(1): e23634.

[5]Tian X, Gao Y, Ma W, et al. Establishment of an Inhalation Administration Non-invasive Murine Model for Rapidly Testing Drug Activity against Mycobacterium tuberculosis[J]. bioRxiv, 2024: 2024.02. 27.582260.

[6]Liu L, Tang Z, Zeng Q, et al. Transcriptomic Insights into Different Stimulation Intensity of Electroacupuncture in Treating COPD in Rat Models[J]. Journal of Inflammation Research, 2024: 2873-2887.

[7]Dong Y, Dong Y, Zhu C, et al. Targeting CCL2-CCR2 signaling pathway alleviates macrophage dysfunction in COPD via PI3K-AKT axis[J]. Cell Communication and Signaling, 2024, 22(1): 364.

[8]Shen S, Huang Q, Liu L, et al. GATA2 downregulation contributes to pro-inflammatory phenotype and defective phagocytosis of pulmonary macrophages in chronic obstructive pulmonary disease[J]. Aging (Albany NY), 2024, 16(19): 12928.

[9]Zou X, Huang Q, Kang T, et al. An integrated investigation of mitochondrial genes in COPD reveals the causal effect of NDUFS2 by regulating pulmonary macrophages[J]. Biology Direct, 2025, 20(1): 4.

[10]Tian X, Gao Y, Li C, et al. A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis[J]. Frontiers in Pharmacology, 2025, 15: 1400436.

[11]Liu K, Liu R, Zhang C, et al. Suzi Daotan Decoction alleviates asthmatic airway remodeling through the AMPK/SIRT1/PGC-1α signaling pathway and PI3K/AKT signaling pathway[J]. Scientific Reports, 2025, 15(1): 6690.

[12]Huang Q, Kang T, Shen S, et al. Extracellular vesicular delivery of ceramides from pulmonary macrophages to endothelial cells facilitates chronic obstructive pulmonary disease[J]. Cell Communication and Signaling, 2025, 23(1): 124.

[13]Zeng H, Liu X, Liu P, et al. Exercise's protective role in chronic obstructive pulmonary disease via modulation of M1 macrophage phenotype through the miR-124-3p/ERN1 axis[J]. Science Progress, 2025, 108(3): 00368504251360892.


此介绍及参数为产品基础信息，可能滞后于产品更新，具体参数请与我司联系。